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As for women, the androgenic properties of oxandrolone can improve virilization symptoms. Sexual side effects including decreased ejaculatory volume and low sperm counts have occurred in patients receiving long-term therapy or excessive doses. In 2003, Catlin received a used syringe containing a residual substance tetrahydrogestrinone (THG), which he identified, synthesized by hydrogenation of gestrinone and a developed specific method of detection. Letrozole selectively oral steroids UK inhibits gonadal steroidogenesis but has no significant effect on adrenal mineralocorticoid or glucocorticoid synthesis.

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